Scientists map the cellular blueprint that sculpts every human face
A new single-cell and spatial atlas of the developing human face identifies 56 cell states, hundreds of spatial patterning genes ...
Tag: enhancers
How Embryos Police the Evolution of Duplicated Genes in Salmon
A massive multiomics study of Atlantic salmon and rainbow trout shows that developmental constraints, particularly at the vertebrate phylotypic period, ...
AI Learns the Hidden DNA Code That Marks Enhancers Across Species
A new interpretable deep learning framework called EnhancerDetector identifies gene enhancers from DNA sequence alone across species from human to ...
Gene Activity Comes in Bursts: Epigenetics Reshapes the Picture of Transcriptional Noise
A new review argues that transcription occurs in multi-scale bursts shaped by DNA methylation, histone variants, modifications and enhancer looping, ...
Wax Moth Larvae Yield First Genome-Wide Map of Transcription Start Sites During Fungal Infection
Researchers have built the first genome-wide atlas of transcription start sites in the greater wax moth, mapping promoter activity during ...
Enhancers That Free Stalled Polymerase Drive Tumor-Feeding Macrophages Across Cancers
A pan-cancer single-cell epigenetic study reveals that tumor-supportive macrophages arise through distinct enhancer-driven trajectories in which releasing paused RNA polymerase ...
Open Chromatin Is Not So Open: Active Genes Ride on Condensed Domains
New simulations reveal that euchromatin is mostly condensed into dense domains, with short active regulatory regions protruding on their surfaces ...
Reading the Genome One Molecule at a Time: A Practical Guide to Single-Molecule Genomics
Leading genome researchers have published a practical guide in Nature Reviews Molecular Cell Biology explaining how single-molecule genomics can reveal ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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