Hidden Vascular Flaw in PCOS Emerges Only When Blood Sugar Rises
Endothelial cells derived from women with PCOS harbor a latent mitochondrial defect that hyperglycemia unmasks, and blocking the enzyme myeloperoxidase ...
Tag: endothelial dysfunction
Why Blockbuster Drugs Fail the Microvessels: Herbal Multi-Target Chemistry Enters the ANOCA Debate
A new review maps how the interconnected molecular pathology of angina with non-obstructive coronary arteries may demand multi-target therapies that ...
Lupus quietly doubles down on heart disease, and standard risk scores miss it
A new Frontiers in Lupus Research Topic shows that cardiovascular risk in systemic lupus erythematosus arises from a complex interplay ...
How Plant Polyphenols May Slow the Arterial Damage Behind Heart Attacks and Stroke
A new review in Molecular Biology Reports maps how dietary polyphenols such as resveratrol, quercetin, catechins, curcumin and anthocyanins target ...
Sepsis May Leave Tissues Primed for Cancer, Review Argues
A new review in the Journal of Translational Medicine argues that sepsis may remodel tissues through an Immuno–Vascular–Matrix Triad in ...
Itchy Skin Disease Linked to Higher Rates of Erectile Dysfunction in Large US Study
A large NIH All of Us analysis found that men with prurigo nodularis had significantly higher odds of erectile dysfunction, ...
Gentle Ultrasound and Microbubbles Repair Diabetic Kidney Damage in Mice
A new study shows that low-intensity ultrasound combined with clinical microbubble agents reverses endothelial dysfunction and improves kidney function in ...
Blood Fats and Fat-Cell Hormones Join Forces to Predict Diabetic Eye Disease
Researchers in China built a prediction model combining adipokines such as omentin-1 and adiponectin with red cell distribution width and ...
Vascular Receptor TLR4 Emerges as a Master Switch Between Vascular Aging and Targeted Senotherapeutics
A new review in Aging Cell positions endothelial TLR4 as a context-dependent molecular rheostat controlling vascular senescence, arguing that precision ...
Calpain Blocker Restores Cellular Cleanup Crew and Protects Blood Vessels in Diabetes
A new study shows that overactivated calpains block autophagy and mitophagy in endothelial cells under high glucose, and that inhibiting ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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