Old Immunosuppressant Drug Found to Kill Aging Cells and Block Cancer
Researchers found that the immunosuppressant cyclosporine A selectively kills senescent cells by triggering endoplasmic reticulum stress and paraptosis-like death, preventing ...
Tag: endoplasmic reticulum stress
Faulty Calcium Bridge Between Cell Powerhouses Drives Skin Barrier Breakdown in Eczema
Researchers have shown that the atopic dermatitis risk protein TMEM232 overloads the calcium bridge between the endoplasmic reticulum and mitochondria, ...
Small Cell Lung Cancer Relies on Targetable Nonsense-Mediated Decay for Immune Control
A Hidden RNA-Decay System May Be the Achilles’ Heel of Small-Cell Lung Cancer Small-cell lung cancer, one of the most ...
SELENOF and unfolded protein response crosstalk determines breast epithelial cell fate
A newly published study is drawing attention to an intricate molecular conversation inside breast epithelial cells: the crosstalk between SELENOF, ...
Diet Drives RKIP Loss, Disrupts Liver Lipid Balance
In a groundbreaking study published in Nature Communications, researchers have unveiled a novel molecular mechanism linking dietary habits to the ...
Neocarzilin A Triggers ER Stress to Induce Apoptosis
In a groundbreaking study poised to revolutionize our understanding of cellular stress responses and apoptosis, researchers have unveiled the potent ...
NOXA Drives Disc Degeneration via ER Stress Activation
Recent advances in cellular and molecular biology have unveiled critical insights into the mechanisms underlying intervertebral disc degeneration (IDD), a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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