Scientists Uncover Molecular Switch That Helps Prostate Cancer Spread to Bone
A new study reveals that an AURKA-driven phosphorylation and SUMOylation cascade stabilizes the protein SPICE1, fueling prostate cancer's spread to ...
Tag: EMT
Cellular Freight Protein YKT6 Emerges as a Driver of Lung Cancer Growth
A new study finds that the vesicle-trafficking SNARE protein YKT6 is overexpressed in lung cancer, where it drives proliferation and ...
Misplaced Gap Junction Protein Drives Colorectal Cancer Spread—and Reveals a Drug Weakness
Researchers found that the gap junction protein Cx26 relocates to mitochondria in metastatic colorectal cancer, driving EMT and calcium signaling, ...
Atypical B Cells Emerge as Key Players in Gastric Cancer Spread, Study Finds
A large computational study links TTN/TP53 co-mutations in gastric cancer to a prognostically favorable population of tumor-associated atypical B cells ...
CD39 Emerges as a Deadly Biomarker and Drug Target in Bile Duct Cancer
New research shows that the immune enzyme CD39 is overexpressed in cholangiocarcinoma, drives tumor growth and metastasis through the ANXA2 ...
Sudden Stress Surges, Not Chronic Load, Push Cancer Cells Toward Invasive Growth, MRI-Tracking Sensors Reveal
A new MRI-readable nanoparticle sensor shows that abrupt surges of mechanical stress, rather than cumulative load, trigger epithelial–mesenchymal transition in ...
Scientists Uncover Hidden Feedback Loop That Drives Colon Cancer Spread
A newly mapped SFRP2–Snai1–USP11 feedback loop stabilizes a key metastasis protein and activates PI3K/AKT/mTOR signalling, revealing fresh targets against colon ...
Chemical Tags on RNA Drive Cancer Spread and Treatment Failure, Review Finds
A comprehensive review in Molecular Cancer details how chemical modifications to RNA molecules regulate tumor metastasis and therapy resistance, opening ...
Enzyme GDH1 Keeps Breast Cancer Persister Cells Alive During Chemotherapy
New research shows that the mitochondrial enzyme GDH1 sustains drug-tolerant persister cells in triple-negative breast cancer by coordinating glutamine metabolism, ...
Tiny Sensors That Catch Cancer Cells in the Blood Are Racing Toward the Clinic
A new review details how electrochemical biosensors are being engineered to detect rare circulating tumor cells and ctDNA, bringing minimally ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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