Sequencing cohorts link genomic features to survival in early-stage lung cancer
A clinical sequencing study associated tumor mutation burden, whole-genome doubling and mutations in four genes with worse survival in early-stage ...
Tag: EGFR
Deep CT model stratifies EGFR and TP53 mutation groups in lung adenocarcinoma
A retrospective study found that a deep-learning model combining CT images with clinical and semantic features could classify five EGFR ...
Mebendazole restores gefitinib activity by inducing DNA damage in resistant lung cancer cells
Mebendazole combined with gefitinib increased DNA damage and suppressed growth in preclinical models of gefitinib-resistant non-small cell lung cancer.
Review maps NSCLC-to-SCLC transformation amid expanding lung cancer treatments
A 2026 literature review synthesizes clinical, diagnostic, molecular and therapeutic evidence on transformation from non–small cell lung cancer to small ...
Computational study prioritizes two benzohydrazide derivatives for EGFR testing
A computational and synthesis study prioritized benzohydrazide compounds 3d and 3f for experimental EGFR testing, while the lack of biological ...
Resistance Training Tops Kidney Benefits in Diabetic Disease, But Evidence Remains Fragile
A network meta-analysis of 20 randomized trials finds resistance training showed the largest kidney function gains in non-dialysis diabetic kidney ...
EGFR Co-Targeting with Nanocarriers Offers New Precision Path for Triple-Negative Breast Cancer
A new review in Genes & Diseases outlines how co-targeting EGFR alongside other tumor-driving molecules, delivered via nanocarriers, could enable ...
Massive Turkish Genome Study Maps Hidden Mutation Patterns in Advanced Lung Cancer
A 1,500-patient next-generation sequencing study from Gazi University reveals EGFR and KRAS as dominant drivers in advanced NSCLC, with distinct ...
Cancer’s Hidden Fingerprints: Tumor DNA Found in Body Fluids Beyond Blood
A new study shows that sequencing tumor DNA in ascites, pleural fluid, cerebrospinal fluid, and pericardial effusions can detect malignancies ...
Two-in-one boron compound fights tumors and powers neutron capture therapy
A carborane-quinazoline hybrid derived from erlotinib delivered boron to tumor cells far more efficiently than BPA and delayed tumor growth ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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