Review Maps HOX Gene Roles in Breast Cancer Therapy
A review published in Discover Oncology examines the epigenetic dysregulation of HOX genes in breast cancer, integrating findings from clinical ...
Tag: dysregulation
Emotion Dysregulation Linked to Poorer Sleep in Late Pregnancy
A longitudinal study in the Journal of Clinical Sleep Medicine finds that high emotion dysregulation is associated with worse subjective ...
TP53 Alterations in Wilms Tumor Linked to Poorer Patient Survival
An integrative clinico-genomic analysis indicates that TP53 alterations occur in approximately 2% of Wilms tumor cases and are associated with ...
Plasma microRNA signature identified in treatment-naïve primary progressive multiple sclerosis
An exploratory case-control study identified 24 plasma microRNAs with corrected-significant differences in treatment-naïve primary progressive multiple sclerosis patients.
mTORC1 may act as a transition switch in ME/CFS post-exertional malaise
A new review proposes mTORC1 as a transition switch linking mitochondrial dysfunction to post-exertional malaise in ME/CFS, while noting that ...
UK survey links cognitive distortions, not emotion dysregulation, to IED violence
A cross-sectional UK survey of 791 adults found that cognitive distortions, but not emotion dysregulation, statistically mediated the association between ...
Lysosomal pH emerges as a context-dependent amplifier in septic lung injury
A review identifies lysosomal pH dysregulation as a plausible context-dependent amplifier of sepsis-associated lung injury, but finds that most supporting ...
AI Model Flags Septic Shock Risk in Appendicitis Patients
A multicenter machine learning study of 3,000 appendicitis patients shows that routine blood indices and ultrasound signs of barrier failure ...
Metabolic Blood Test Pattern May Predict Post-Stroke Depression Risk
Post-stroke depression (PSD) is one of the most common neuropsychiatric complications among stroke survivors, significantly affecting rehabilitation adherence and long-term ...
Rare Gene Mutation Rewires Developmental Programs in Alazami Syndrome, Revealing Cardiac Risk
In a finding that could reshape how clinicians think about one of the rarest neurodevelopmental disorders on record, a team ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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