Diabetic Retinopathy Rewritten as a Stage-by-Stage Signaling Map
Diabetic retinopathy has long been treated in clinics as a disease of leaky blood vessels, but a new review argues ...
Tag: dysfunction
S-adenosylmethionine ameliorates spermatogenic dysfunction and sperm DNA damage via transsulfuration pathway
Male infertility has quietly become one of the defining reproductive health challenges of our time, affecting roughly 17.5 percent of ...
Toad Venom Compound Cinobufagin Disables Liver Cancer Cells by Shutting Down Their Peroxisomes
A team in China reports that cinobufagin, the main antitumor component of traditional Chansu venom, collapses peroxisome biogenesis in liver ...
Gramicidin A shields Parkinson’s cell model from oxidative damage
A molecule best known for punching holes in bacterial membranes may have an unexpected second life as a neuroprotective agent. ...
Blood protein surge after liver reperfusion may flag early transplant graft failure
A UCSF team tracked pentraxin-3 through liver transplant surgery and found that the speed of its rise after reperfusion, not ...
One in Eight Monitored Patients Show Thyroid Damage After PD-1 Immunotherapy
Immune checkpoint inhibitors have transformed the outlook for many patients with advanced cancer, but the same immune reawakening that lets ...
How Broken Brain Networks and Molecular Chaos Drive Major Depression
A sweeping integrative review argues that major depressive disorder arises from interacting molecular dysregulation and large-scale brain network dysfunction, while ...
Hidden Heart Damage: Nearly Half of Aortic Stenosis Patients Show Microvascular Disease Before Valve Replacement
A new systematic review finds that coronary microvascular dysfunction affects roughly one-third to one-half of severe aortic stenosis patients before ...
Micro- and nanoplastics emerge as immunological Trojan horses in viral disease
Microplastics and nanoplastics have now been detected in virtually every environmental compartment on Earth, from marine sediments and freshwater systems ...
Radiation-Free Ultrasound Urodynamics Detect Hidden Reflux in Children’s Neurogenic Bladders
For children whose bladders misbehave because their nervous systems do, the stakes of a routine diagnostic exam are quietly enormous. ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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