Tag: drug repurposing

In a rat model of paraquat-induced kidney damage, the approved drug disulfiram reduced tissue injury, fibrosis, and oxidative stress, with ...

An international team led by RCSI and The Institute of Cancer Research, London, used an AI tool called iPhenMap to ...

An in vitro study found that a repurposed darifenacin-betamethasone formulation reduced the fitted streptomycin IC50 by 2.2-fold in a resistant ...

A zebrafish study finds that gabapentin, already used for alcohol withdrawal, reduced hepatic steatosis, intestinal inflammation, and il8 expression after ...

An editorial reviewing 21 contributions argues that sepsis therapy is shifting from broad cytokine suppression toward phenotype- and timing-based treatments ...

A laboratory study found that ivermectin weakened cisplatin-associated cytotoxicity, apoptosis and S-phase arrest in HN9 oral cancer cells.

New research shows that inhibiting mitochondrial complex I kills Theileria annulata-infected cells, including drug-resistant ones, and reveals a conserved mitochondrial ...

A Bayesian multi-omics analysis of GWAS and blood and brain QTL data has identified 86 gene-protein associations across nine neuropsychiatric ...

A randomized Swedish trial found that oral salbutamol, a common asthma medication, improved motor function, walking distance, grip strength, and ...

Rockefeller University researchers found that the common blood pressure drug losartan stimulates metabolically active brown fat in mice and is ...