Lipid Metabolism Emerges as a Central Driver of Drug Resistance in Aggressive Lymphoma
A new review argues that lipid metabolic reprogramming acts as a convergence node for treatment resistance in aggressive non-Hodgkin lymphoma, ...
Tag: drug repurposing
Dogs May Not Respond to Thalidomide, Genetic Study Warns
Genomic analysis of nearly 2,000 dogs reveals that they carry the same cereblon variation that makes mice insensitive to thalidomide, ...
Arthritis Drug Diacerein Shows Surprising Power Against Deadly Brain Cancer
Researchers report that the osteoarthritis drug diacerein kills glioma cells by triggering caspase-3 and GSDME-mediated pyroptosis, revealing a new drug-repurposing ...
Symptomatic Treatments Remain Central to Alzheimer’s Care as New Evidence Emerges
A major new review finds that symptomatic therapies for Alzheimer disease, from cholinesterase inhibitors to personalized psychosocial care, deliver meaningful ...
Alcoholism Drug Disulfiram Restores Fluconazole Power Against Resistant Candida
Egyptian researchers found that the alcohol-aversion drug disulfiram synergizes with fluconazole, downregulates the Cdr1 efflux pump, and inhibits biofilm formation ...
RNA Acetylation Enzyme NAT10 Helps Glioblastoma Resist Radiotherapy
Researchers found that the RNA acetyltransferase NAT10 helps glioblastoma resist radiotherapy by stabilizing SLC7A11 mRNA and blocking immunogenic ferroptosis, and ...
Common Painkillers Show New Promise in Cancer Prevention and Treatment
A new review synthesizes decades of evidence showing that selective COX-2 inhibitors can suppress tumor initiation, growth and immunotherapy resistance ...
New Research Reveals Connection Between Antibiotics, Vaccinations, and Anti-Inflammatory Medications in Lowering Dementia Risk
Recent research involving health data from over 130 million individuals has uncovered a promising link between the use of certain ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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