Tag: drug repurposing

Researchers in Iraq report that the anti-diabetic drug sitagliptin modulates the vanA and blaTEM resistance genes in multidrug-resistant Enterococcus faecalis ...

A new correspondence in Molecular Biology Reports highlights evidence that the adiponectin receptor agonist AdipoRon promotes angiogenesis in B-cell leukemia ...

New research shows that the calcium channel blocker diltiazem suppresses parthanatos-related DNA damage and poly(ADP-ribose) accumulation in patient-derived cells from ...

An integrative omics study of Tritrichomonas foetus has identified hundreds of drug-target candidates, most of which belong to protein families ...

A new study in Neurocritical Care links GLP-1 receptor agonist use to improved survival in patients undergoing surgery for traumatic ...

Researchers report that the steroid sulfatase inhibitor irosustat and its target molecule cholesterol sulfate inhibit drug-resistant Plasmodium falciparum through a ...

Researchers report that the antibiotic clofoctol redistributes CD8-positive T cells from the bone marrow and enhances their tumor-killing activity, substantially ...

Researchers report that the repurposed alcoholism drug disulfiram exploits a collateral vulnerability in chemotherapy-resistant ER+ breast cancer cells, and that ...

A phase 2b European trial found that SOM3355, a repurposed beta-blocker with a novel triple mechanism, significantly reduced chorea in ...

A new study shows that the decades-old contraceptive drug ormeloxifene drives breast cancer cells into irreversible senescence and enhances their ...