Yeast Genetics Map How Thousands of Variants Reshape the Protein Interactome
A large-scale study in budding yeast has mapped how roughly 12,000 natural genetic variants reshape the strength of protein–protein interactions ...
Tag: drug mechanisms
Kinase Inhibitors Trigger Surprising Non-Catalytic Effects by Displacing Autoinhibitory Domains
A multimodal proteomics study shows that ATP-competitive kinase inhibitors displace autoinhibitory domains, driving unexpected non-catalytic functions relevant to drug development.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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