Tag: drug discovery

A scientific review details advancements in stem cell-derived brain organoids for disease modeling and drug screening alongside critical challenges in ...

Researchers identified benastatin B from earthworm gut bacteria, showing potent bactericidal activity against vancomycin-resistant Enterococcus faecalis.

A new AI framework called MolMMP improves molecular toxicity prediction by integrating SMILES sequences, graph topology, and 3D geometric data.

A computational study of Annona muricata fruit phytochemicals identifies spathulenol, caryophyllene oxide and bornyl acetate as the strongest predicted binders ...

Researchers repurposed regulatory rodent toxicity archives to identify 27 chemical compounds associated with increased survival, highlighting mitochondrial stress responses as ...

Volume 43 of SLAS Discovery presents AI-guided screening, automated platforms and new cell-based assays that accelerate drug discovery across infectious ...

Adding pyridine to a Zn-ProPhenol-catalyzed hydrophosphineization of chromones reverses product chirality by shifting the catalyst between dimer and monomer forms, ...

A comprehensive literature review reveals that fungal endophytes residing within medicinal Apiaceae plants produce structurally diverse secondary metabolites with significant ...

Researchers have developed GraphPepTox, a geometric deep learning framework that models spatial residue relationships to improve peptide toxicity prediction.

A structure-based molecular docking study evaluated nine phytochemicals from Siddha-associated medicinal plants against the SARS-CoV-2 main protease, identifying distinct polar ...