Stem Cell Models to Reveal Why Parkinson’s Disease Hits Women Differently
Critical Path Institute and the University of Arizona have launched a two-year collaboration using human stem cell-derived neurons and new ...
Tag: drug development
New Drug Candidates Starve Cryptosporidium Parasites by Blocking Their Energy Supply
Researchers engineered 1,440 derivatives of an anti-Cryptosporidium compound and identified two potent lactate dehydrogenase inhibitors that clear the parasite in ...
Bridging the Lab and the Clinic: Why Addiction Science Needs Translational Research
A new commentary in the Journal of Translational Medicine argues that refined animal models and emerging tools like rodent fMRI ...
Iron, Inflammation, and a Deadly Paradox: Rethinking Cancer Wasting Through Ferroptosis
A new iScience review argues that ferroptosis, an iron-driven form of cell death, links tumor and immune signals to muscle ...
Gut diseases in miniature: organoids and organ-on-a-chip models reshape gastrointestinal research
A Nature Biomedical Engineering review synthesises how organoids and organ-on-a-chip technologies are transforming the modelling of inflammatory, infectious and neoplastic ...
Human Organs on Chips Recreate Body’s Niches to Predict Drug Safety
A Stanford-led review in Nature Biomedical Engineering maps how multi-organ tissue chips that preserve each organ's native niche could transform ...
From ocean to pharmacy: marine sugars emerge as next-generation drug candidates
A new review in Glycoscience & Therapy charts how structurally unique marine carbohydrates, from seaweed sulfated polysaccharides to sponge-inspired drugs ...
£4.5 Million UK Aid Partnership Targets Fungal-Scale Burden of Filarial Diseases
Liverpool School of Tropical Medicine has launched a £4.5 million UK aid-funded partnership, ENDPOINT, to develop new diagnostics and treatments ...
Experimental Drug DNL343 Fails to Slow ALS Progression in Randomized Trial
A randomized clinical trial in JAMA Network Open found that 200 mg per day of DNL343, an eIF2B activator, did ...
Anti-Amyloid Drugs for Alzheimer’s Face a Reckoning Over What ‘Benefit’ Really Means
A new Journal of Neurology Comment argues the Alzheimer's field has avoided honestly assessing whether licensed anti-amyloid drugs deliver clinically ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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