Liquid Droplets Inside Cells Emerge as Promising New Targets for Cancer Therapy
A new review details how dysregulated liquid–liquid phase separation drives cancer and how engineered peptides, modification mimics and synthetic condensates ...
Tag: Drug delivery
Pharmacokinetic Modeling Emerges as Key to Unlocking Nanoparticle Medicines
A new review argues that pharmacokinetic modeling frameworks such as PBPK, PopPK, and the proposed MIND workflow can bridge the ...
AI Is Rewriting How Nanoparticle Medicines Are Designed
A new Nature Reviews Bioengineering review details how machine learning is transforming nanoparticle drug delivery design, from formulation optimization and ...
Date Seed Waste Transformed Into Antimicrobial Nanofibers for Controlled Drug Delivery
Researchers have converted discarded Sukkary date seed oil into antimicrobial core-shell nanofibers that load ciprofloxacin with high efficiency and release ...
Scientists propose new blueprint to model and reverse atrial fibrosis in AF
A new review proposes a staged, evidence-bound framework combining patient-specific iPSCs, atrial microphysiological systems and nanomedicine to model and potentially ...
Plant Nanoparticles Deliver a Protein-Degrading Drug That Strikes Colorectal Cancer
Scientists have engineered a PROTAC molecule that destroys the RARα protein and delivered it via Polygonatum sibiricum exosome-like nanoparticles, markedly ...
Metal-Organic Framework Wrapper Makes Ceftazidime Potent Against Resistant Urinary Infections
Researchers have encapsulated the antibiotic ceftazidime in a ZIF-8 metal-organic framework nanocarrier that dramatically improves treatment of Pseudomonas aeruginosa urinary ...
Self-Assembling Carriers Could Redefine How Drugs Reach Their Targets
A new review in the Journal of Advanced Research details how self-assembling delivery platforms built from peptides, polyelectrolytes and natural ...
Engineered Exosomes Loaded With RNA Motifs and Boosted by Rab4 Aim to Trigger Ferroptosis in Endometrial Cancer
Scientists have engineered exosomes that use natural RNA-sorting motifs and Rab4-boosted production to deliver ferroptosis-inducing shRNAs directly to endometrial tumors.
Journal of Pharmaceutical Investigation Records Q1 Ranking as Impact Factor Reaches 5.5
The Journal of Pharmaceutical Investigation has been indexed in the Science Citation Index Expanded since 2021 and achieved a 2022 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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