Hidden Genome Folds Silence Two Tumor-Suppressing Genes in Aggressive Breast Cancer
Researchers have discovered that DNA methylation evicts the architectural protein CTCF from the HOXD locus, collapsing a chromatin loop that ...
Tag: DNA Methylation
Talk Therapy for Insomnia May Slow Biological Aging in Older Adults
A UCLA Health randomized controlled trial found that cognitive behavioral therapy for insomnia increased remission rates and slowed the pace ...
Blood Test Reads DNA Methylation Patterns to Help Detect Deadly Esophageal Cancer
A large two-cohort study shows that a blood-based DNA methylation panel targeting the HYAL2, S100P and DYRK4 genes, combined with ...
Epigenetic Aging Clocks Reveal How Stroke Accelerates Cognitive Decline
A large longitudinal study shows that DNA methylation-based biological aging and the cytokine TGF-beta play distinct causal roles in cognitive ...
Diseased Kidneys Age Faster at the Cellular Level, Single-Cell Epigenome Atlas Reveals
A cross-species single-cell epigenome atlas shows that kidney disease accelerates epigenetic aging most dramatically in tubular epithelial cells, which lose ...
Tiny Alga’s Oddball Chromosomes Live in Their Own Private Nuclear Neighborhoods
The first Hi-C analysis of the tiny alga Ostreococcus tauri shows that its enigmatic low-GC outlier chromosomes fold into sharply ...
Genes and Epigenetics Converge to Explain Sudden Cardiac Death Without Family History
A new review maps how common genetic variants, insertion/deletion polymorphisms, microRNAs, DNA methylation and histone modifications together shape the risk ...
First Mosaic Case Rewrites the Genetic Story of a Rare Overgrowth Syndrome
Researchers report the first known case of Cohen–Gibson syndrome caused by a mosaic EED variant, expanding the mutational spectrum of ...
Crushing Rice Seeds Under Pressure Leaves Genetic Scars That Last Nine Generations
A rice lineage derived from seeds treated with 100 megapascals of hydrostatic pressure still shows reduced height, tiller number, and ...
Teeth Without Pulp Can Still Reveal a Person’s Age Through DNA Methylation
Chinese researchers show that DNA methylation patterns in pulp-free teeth can estimate a person's age with a mean error of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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