Three sequencing methods tested on archival breast tumor DNA methylation
Researchers showed that whole-genome bisulfite sequencing, EM-seq, and the biomodal evoC kit are all feasible for DNA methylation profiling of ...
Tag: DNA methylation profiling
Nanopore Sequencing Delivers Full Pediatric Brain Tumor Workup in a Single Assay
A retrospective study of 20 pediatric CNS tumors found long-read nanopore sequencing matched methylation arrays for copy-number profiling and tumor ...
Scientists Discover PINNED, a Previously Unrecognized Tumor of the Pineal Gland
Researchers have identified a previously unrecognized pineal gland tumor type, provisionally named PINNED, defined by a unique DNA methylation signature ...
Custom-Built DNA Cutting Recipe Cracks the Code of Plant Epigenetics
A new in silico design framework optimizes epi-ddRADseq enzyme pairs and size-selection windows across 75 plant species, showing that species-specific ...
Rare Spinal Cord Tumors Get a Molecular Makeover in New Pediatric Review
A new comprehensive review synthesizes the molecular classification, surgical strategy, and pediatric-specific evidence gaps in spinal ependymoma management.
Old Wax Blocks, New Signals: Phosphoproteomics Adds a Functional Layer to Brain Tumor Diagnostics
Researchers have shown that routine formalin-fixed paraffin-embedded brain tumor tissue yields robust proteomic and phosphoproteomic profiles that recover EGFR-associated signaling ...
Decades-Old Newborn Blood Spots Yield High-Quality DNA Methylation Data With Tiny DNA Inputs
A pilot study shows the Illumina MethylationEPIC v2.0 array produces high-quality DNA methylation data from decades-old Swedish newborn blood spots ...
DNA methylation reveals protocadherin gene silencing drives meningioma progression
Meningiomas, the most common primary brain tumors in adults, have long presented clinicians with a deceptively simple problem: some grow ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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