Cells Read Their Neighbors to Pinpoint Their Own Position in the Embryo
An information-theoretic study shows that gene expression in a cell's immediate neighbors supplies the missing positional information needed to uniquely ...
Tag: developmental biology
The Case of the Missing Mouse Pax6 Neuron: A Cross-Species Mix-Up Rewrites Brain Cell Taxonomy
A cross-species transcriptomic meta-analysis reveals that the mouse Pax6 interneuron subclass was never missing but mislabeled, while the primate Sncg ...
Chimera Crayfish With Two Genomes Stuns Scientists Studying Hybrid Offspring
Researchers in China report a rare chimera in the hybrid offspring of red swamp crayfish, with multiple genotypes coexisting in ...
New AI Framework Puts Tissue Geography Into RNA Velocity and Steers Cell Fates In Silico
A new deep learning and agent-based framework called veloAgent integrates tissue spatial context into RNA velocity inference and enables virtual ...
Cell Shape and Position Predict Fate in a Developing Epithelium
By tracking thousands of cells in live Xenopus embryos and applying machine learning, researchers show that cell shape, position, and ...
Zebrafish Reveal How Polycomb Complexes Sculpt the Heart and Fins
A new review shows that Polycomb repressive complexes PRC1 and PRC2 are essential for zebrafish heart looping, contraction and pectoral ...
Scientists Map the Genetic Symphony of Fish Embryo Development Stage by Stage
A new time-series transcriptomic study of marine medaka embryos reveals a dual-wave program of zygotic genome activation and a transient ...
Tissue Flow Acts as a Guidance Cue for Immune Cell Polarization and Migration
New research in Xenopus embryos shows that flowing ectodermal tissue physically guides the polarization and directional migration of embryonic immune ...
Organoid Study Reveals How WNT2B Mutations Drive Deadly Congenital Diarrhea
Human intestinal organoids reveal that loss of WNT2B disrupts epithelial architecture and stem cell activity, with mesenchymal WNT2B deficiency producing ...
New Cell Atlas Maps How the Newborn Heart Learns to Beat Like an Adult
By combining single-nucleus RNA sequencing with spatial transcriptomics, researchers have built a detailed spatiotemporal atlas of the postnatal mouse heart, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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