Nanobody Degrade System Targets Proteins in Slime Mold
Researchers developed a nanobody-based degron system called dictyGrad-ALFA that enables efficient, cell type-specific protein knockdown in Dictyostelium discoideum, overcoming limitations ...
Tag: developmental biology
Temperature Shapes Wing Size and Spot Patterns in Fruit Flies
A study in Development Genes and Evolution reveals that rearing temperature independently influences wing size and spot size in Drosophila ...
Historical Embryology Concepts Guide Modern Organoid Research
A perspective in Development Genes and Evolution argues that historical concepts from experimental embryology, such as self-differentiation and morphogenetic fields, ...
Large Neuroblasts Build Brain in Simple Chordate
Researchers have identified a specific mode of stem cell division that drives brain formation in Oikopleura dioica , a small ...
Duplicated Zebrafish Cardiac Genes Diverge Through Unique Protein Partner Interactions
Genetic and proteomic analyses in zebrafish demonstrate that duplicated cardiac transcription factors Tbx2a and Tbx2b have evolved non-redundant developmental roles ...
Posterior Hox Gene Expression Explains Appendage Divergence in Tarantulas and True Spiders
Comparative embryonic mapping reveals that divergent regulation of duplicated posterior Hox genes underlies the specialized reduction and modification of opisthosomal ...
Embryonic Stem Progenitors Guide Small Intestine Formation Prior to Villification
Researchers discovered that embryonic intestinal Lgr5-positive cells regulate regional organogenesis and tissue patterning before villus formation through Hedgehog signaling pathways.
Locust Antennal Nerve Study Reveals How Embryonic Sensory Circuits Wire Flight Centers
Researchers mapped how sensory neurons in Johnston’s organ wire into locust brain flight circuits during embryonic development.
Loss of Epigenetic Regulator ASH2L Causes Cleft Palate in Mice
Deleting the epigenetic regulator Ash2l from developing palatal mesenchyme collapses the H3K4me3 histone mark, silences Wnt5b, and produces complete cleft ...
Zebrafish Genome’s Extra Duplicated Genes Reveal Hidden Rules of Gene Function
A review argues that zebrafish's extra round of whole genome duplication 350 million years ago created duplicated gene pairs whose ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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