Tag: cuproptosis

A three-component nanoparticle that consumes tumor glucose and triggers pyroptosis and cuproptosis suppressed liver cancer growth and established immune memory ...

A review in Molecular Biology Reports describes how pro-inflammatory forms of regulated cell death, including ferroptosis, pyroptosis and necroptosis, contribute ...

A new review outlines how the copper-dependent cell death regulator FDX1 may shape prognosis, metabolism, and treatment resistance in triple-negative ...

Researchers built a prognostic model from seven m6A RNA methylation-related genes correlated with cuproptosis genes in colorectal cancer and confirmed ...

An integrated machine-learning and single-cell study identifies ENTPD5 as a context-dependent candidate marker of radioresistance in hepatocellular carcinoma, with prognostic ...

A new review in Medical Oncology details how the mitochondrial transporter SLC25A39 links glutathione import, iron-sulfur cluster assembly and tumor ...

Research reveals that FDX1 downregulation in acute myeloid leukemia drives resistance to cuproptosis via the ROS/p53/ME1 axis, suggesting a new ...

A preclinical study in Molecular Cancer reports that elesclomol and neocuproine trigger mechanistically distinct, FDX1-dependent and FDX1-independent forms of copper-driven ...

A preclinical study links ceruloplasmin and STPG3-AS1 to lipoylation and cuproptosis-associated changes in castration-resistant prostate cancer cells, but it does ...

Preclinical experiments show that METTL14 stabilizes FDX1 RNA through m6A methylation, promoting cuproptosis and suppressing clear cell renal cell carcinoma ...