Why the Brain’s Master Clock Refuses to Reset When Temperatures Shift
A new computational model shows that phase differences between subregions of the suprachiasmatic nucleus explain why the brain's master circadian ...
Tag: computational biology
Cellular Recycling Routes Reshape How Hormone Receptors Send Their Signals
A new computational model shows that a small pool of internalized follicle-stimulating hormone receptors can drive outsized endosomal signaling, revealing ...
Computational Microscope Opens a New Window on Chromatin Folding
An international team has developed OpenCGChromatin, an open-source simulation tool that acts as a computational microscope to reveal how chromatin ...
DyME: A New Engine Automates Thousands of Protein Simulations for Molecular Design
Researchers have developed DyME, an open-source platform that automates high-throughput mutagenesis, molecular dynamics simulation, and comparative analysis of thousands of ...
Flawed Benchmarks Hid AI Success in Gene Perturbation Prediction
A new calibration framework shows that common benchmarking metrics masked real perturbation-specific signal, and that deep learning models can outperform ...
New Standard PEtab Select Brings Order to the Chaos of Choosing Biological Models
A new open standard called PEtab Select brings automated, reproducible model selection to systems biology, enabling researchers to compare billions ...
AI Reads Protein Shapes to Unmask Bacterial Weapons
A new multimodal deep learning framework called GeoEPred combines protein language model semantics with predicted 3D structures to more accurately ...
AI-Designed Protein Binders Face Real-World Test in Landmark CAR T Cell Competition
A crowdsourced competition called Bits to Binders tested 12,000 AI-designed minibinders as CAR T cell recognition domains, revealing both the ...
New AI Server Lets Scientists Analyze Spatial Gene Maps by Simply Asking
Researchers have developed stMCP, a Model Context Protocol server that lets scientists analyze spatial transcriptomics data through natural language while ...
Binary Trees for Cell Fates: New Algorithm Reshapes Single-Cell Trajectory Inference
Researchers in Hong Kong and Japan have developed an integer programming method that constrains single-cell trajectory trees to binary branching, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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