Bispecific Antibody Meets Antibody-Drug Conjugate in Promising Small Cell Lung Cancer Trial
First clinical data from the Phase 1b/2 BNT324-01 trial show that the investigational combination of pumitamig and elfetabart drozuntecan achieved ...
Tag: combination therapy
Symptomatic Treatments Remain Central to Alzheimer’s Care as New Evidence Emerges
A major new review finds that symptomatic therapies for Alzheimer disease, from cholinesterase inhibitors to personalized psychosocial care, deliver meaningful ...
Alcoholism Drug Disulfiram Restores Fluconazole Power Against Resistant Candida
Egyptian researchers found that the alcohol-aversion drug disulfiram synergizes with fluconazole, downregulates the Cdr1 efflux pump, and inhibits biofilm formation ...
Dual Diabetes Drug Therapy Linked to Lower Heart Attack and Stroke Risk
A new meta-analysis finds that combining SGLT2 inhibitors with GLP-1 receptor agonists is associated with lower risks of myocardial infarction ...
Scientists Target the CD73-Adenosine Axis to Break Lung Cancer’s Immune Shield
A new review maps how the CD73-adenosine axis drives immune suppression in non-small cell lung cancer and how blocking it ...
Olaparib Plus Radiotherapy Shows Promise for Boosting Immune Defense Against Oral Cancer
A new mouse study finds that combining the PARP inhibitor olaparib with radiotherapy improves tumor control in oral squamous cell ...
Considerations for Combination Therapies Aiming Disease Modification in Parkinson’s
A new analysis published in npj Parkinson’s Disease considers how combination therapies might better slow or modify Parkinson’s disease—an approach ...
LIG1 Loss Reveals Targetable Weakness Against Chemotherapy-Resistant Triple-Negative Breast Cancer
In triple-negative breast cancer (TNBC) that carries TP53 mutations, loss of one copy of the DNA ligase I gene (LIG1) ...
Revealing the Inverse Relationship of KLRG1 and PD-1 in Tumor Infiltrating CD8 T Cells
In the evolving landscape of cancer treatment, the intricate interaction between immune cells and tumor microenvironments remains a focal point ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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