GIPR Activation Linked to Healthier Dietary Choices
A Mendelian randomization study in BMC Medicine finds that GIPR activation via BMI is causally linked to reduced fatty food ...
Tag: colocalization
Mendelian Randomization Study Identifies Plasma Protein Targets for Macular Degeneration
A multi-omics Mendelian randomization study identified 22 plasma proteins associated with age-related macular degeneration, highlighting four high-confidence therapeutic candidates.
Mitochondrial genes tied to congenital heart disease risk in multi-omics study
A multi-omics Mendelian randomization analysis identified 13 candidate mitochondrial-related genes linked to congenital heart disease susceptibility, with POLG and EARS2 ...
Genome study reveals shared genetic roots of fibrotic diseases
A genome-wide meta-analysis across five cohorts identifies 654 genetic associations and shared pathways linking fibrotic diseases.
Massive Single-Cell Map Reveals How Rare and Common Gene Variants Steer Immunity
Phase 1 of the TenK10K consortium maps common and rare genetic variants affecting gene expression across 28 immune cell types ...
Blood Proteins Linked to Heart Imaging Signatures and Disease Risk in Large UK Biobank Study
A UK Biobank study linked 681 blood proteins to cardiac MRI phenotypes and used genetic analysis to prioritize potentially causal ...
Large Genetic Study Pinpoints Seven New DNA Loci and 23 Proteins Tied to Macular Degeneration
An integrative genomic and proteomic study identified seven new genetic loci and 23 genetically supported plasma proteins for age-related macular ...
Genomic scan points to seven kidney genes, but only one earns diabetes-specific support
An exploratory genomic framework combining Mendelian randomization, kidney-compartment eQTL data, and colocalization identifies seven candidate genes for kidney traits, with ...
New Open-Source Toolset Automates 3D Quantification of Fluorescent Colocalization
Researchers have introduced Bioloc3D, an open-source ImageJ and Python toolset that automates three-dimensional quantification of fluorescent elements and their colocalizations ...
Bisphenol Exposure Linked to Inflammatory Bowel Disease Through RORC Immune Pathway
A combined genetic, computational, and cell-based study identifies RORC as a candidate gene linking bisphenol exposure to inflammatory bowel disease-related ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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