Chromatin Loss Rewires Kidney Cancer Mitochondria, and an Old Drug Can Reverse It
A Nature Communications study shows that loss of the SWI/SNF subunit SMARCD1 drives clear cell renal cell carcinoma through a ...
Tag: clear cell renal cell carcinoma
How a Single Glycolytic Enzyme Decides Whether Cancer Cells Grow or Senesce
A new study in Advanced Science shows that losing the glycolytic enzyme TPI1 causes DHAP to accumulate and activates a ...
Kidney Cancer Gene Marker CTDNEP1 Signals Survival Differently Across Tumor Subtypes
Researchers in Japan found that high expression of the CTDNEP1 gene predicts poorer survival in clear cell renal cell carcinoma ...
Tight Junction Protein Revealed as Hidden Brake on Kidney Cancer Growth
Researchers report that the tumor-suppressive protein TJP2 stabilizes TIMM21, which boosts SPRY4 and dampens ERK1/2 signaling to restrain clear cell ...
Blood Test Clues: Six DNA Methylation Markers Flag the Most Common Kidney Cancer
Japanese researchers have identified six hypomethylated CpG sites in blood DNA that distinguish clear cell renal cell carcinoma patients from ...
CASP9 Emerges as a Double-Edged Gene in Kidney Cancer, Study Finds
A multi-omics study identifies CASP9 as a genetically protective but stage-dependent prognostic factor in clear cell renal cell carcinoma, linking ...
Ribosomal Protein RPL28 Emerges as a Driver and Prognostic Marker in Kidney Cancer
New research shows that the ribosomal protein RPL28 is overexpressed in clear cell renal cell carcinoma, where it independently predicts ...
Rare Bladder Metastasis From Kidney Cancer Emerges After Targeted Therapy Fails
Clinicians in China report an extraordinarily rare case of clear cell kidney cancer spreading to the bladder without symptoms after ...
Neurexophilin 4 Emerges as a Molecular Driver of Kidney Cancer Through PI3K/AKT-Controlled Glycolysis
New research reveals that the protein neurexophilin 4 drives the growth, invasion and metabolic reprogramming of clear cell renal cell ...
New Open-Source Tool MetaProViz Turns Raw Metabolomics Data Into Mechanistic Hypotheses
An open-source R package called MetaProViz standardises metabolomics analysis, resolves ambiguous metabolite annotations and links metabolic changes to mechanistic hypotheses, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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