Rare Immune Gene Defect Unmasked by Incomplete Kawasaki Disease in a Young Child
A Malaysian case report describes the first known instance of incomplete Kawasaki disease serving as the initial presentation of genetically ...
Tag: class switch recombination
Hidden Enzyme in B Cells Emerges as a Master Switch for Allergic Asthma
Deleting the Ssu72 phosphatase specifically in B cells sharply reduces IgE and IgG1 production and lung inflammation in a mouse ...
Two Rival Gene Networks Decide Whether B Cells Become Antibody Factories or Memory Makers
Single-cell mapping of human B cell activation reveals that memory cells are intrinsically biased toward becoming plasma cells while naive ...
Histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity
New research in Nature shows that the histone readers MLLT1 and MLLT3 license the antibody-mutating enzyme AID at specific genomic ...
Inside the Germinal Center: How T Follicular Helper Cell Subsets Shape Immunity in Health and Disease
A new review in the Journal of Molecular Medicine maps how heterogeneous follicular helper T cell subsets are regulated by ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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