Baseline kidney function predicts renal decline in urothelial cancer chemotherapy study
A retrospective study of 86 patients with advanced urothelial carcinoma found that baseline kidney function, rather than chemotherapy regimen, was ...
Tag: cisplatin
Protocol plans randomized comparison of kidney-protective drugs during HIPEC
A planned 90-patient randomized trial will compare cilastatin with sodium thiosulfate for preventing acute kidney injury during cisplatin-based HIPEC, but ...
Ivermectin blunts cisplatin effects in oral cancer cells
A laboratory study found that ivermectin weakened cisplatin-associated cytotoxicity, apoptosis and S-phase arrest in HN9 oral cancer cells.
Silent Interferon Signals May Flag Ovarian Tumors That Shrug Off Chemotherapy
A cautious reanalysis of single-cell, TCGA, MRI, and cell-line data links muted type-I interferon signaling and altered cell-state programs to ...
Immunotherapy-boosted chemo shows striking early results against high-risk nasopharyngeal cancer
A prospective phase II pilot study from non-endemic Sichuan reports 95.2 percent response rates and 80 percent event-free survival at ...
Gene Signature Linked to Metastasis May Predict Gastric Cancer Chemotherapy Response
A new study links a gene and microRNA co-expression pattern to both metastatic spread and chemotherapy response in gastric cancer, ...
Cisplatin and Oral S-1 Show Feasibility in Cancer Patients with Severe Liver Dysfunction
A seven-year prospective trial shows that oral S-1 plus cisplatin preserves overall 5-FU exposure and manageable toxicity in cancer patients ...
Programmable RNA demethylation re-sensitizes bladder cancer to cisplatin
Cisplatin-based chemotherapy remains a cornerstone of treatment for advanced bladder cancer, yet resistance to this platinum drug severely limits its ...
Small RNA Molecule Shows Promise Against Ovarian Cancer Chemoresistance
A new study shows that the microRNA-197-3p molecule, which is depleted in ovarian cancer, directly suppresses the collagen protein COL4A6 ...
Rare Eye Complication Emerges After Combined Cisplatin and Capecitabine Chemotherapy
A case report from Beijing describes a 50-year-old woman who developed rare bilateral optic disc edema with papillophlebitis-like features after ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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