Cryo-electron microscopy captures RNA polymerase II remodeling cisplatin-induced DNA interstrand crosslinks into a novel conformation that blocks the active site, ...
New research shows the proteasome inhibitor bortezomib kills cutaneous T-cell lymphoma cells through ROS-dependent mitochondrial apoptosis while suppressing the SKP2-p21/p27 ...
Chemists have synthesized five dimethyltin cinnamate complexes featuring a ladder-like Sn4O4 core, with the lead compound showing potent, selective anticancer ...
A nationwide survey of 120 Chinese physicians reveals that most patients with advanced biliary tract cancer never receive guideline-recommended immunotherapy ...
For the first time, doctors used electrochemotherapy in a child with high-risk neuroblastoma and achieved durable elimination of the drug-resistant ...
A new rat study shows that protocatechuic acid, a natural plant-derived phenolic compound, protects testicular tissue from cisplatin-induced oxidative damage ...
A new study shows that the developmental transcription factor PAX9 acts as a tumour suppressor in oral squamous cell carcinoma ...
A genome-wide CRISPR interference screen has identified the conserved bacterial homologous recombination pathway, and the RecA protein in particular, as ...
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