Modern Arc Radiotherapy Keeps More Saliva Flowing After Head and Neck Cancer Treatment
A clinical study finds that patients treated with VMAT had roughly double the salivary flow and oral moisture of those ...
Tag: cisplatin
Immunotherapy Boost for Bile Duct Cancer Survival Holds Firm After Three Years
Three-year follow-up of the phase 3 KEYNOTE-966 trial confirms that adding pembrolizumab to gemcitabine and cisplatin chemotherapy maintains a durable ...
High Blood Pressure Raises Kidney Injury Risk During Modern Cisplatin Chemotherapy
A Japanese retrospective study of 244 thoracic cancer patients finds that baseline hypertension triples the risk of cisplatin-induced kidney injury ...
Weekly or Every-Three-Week Cisplatin? Trial Finds Similar Acute Toxicity Burden in p16-Negative Head and Neck Cancer
The Phase II portion of the NRG-HN009 trial found that weekly cisplatin did not significantly reduce acute toxicity compared with ...
When Chemotherapy Drains the Body’s Salt: A Rare Brain Tumor Relapse Case Explained
A Japanese case report details how salvage chemotherapy for a brain germinoma relapse twelve years after childhood treatment triggered severe, ...
Ligand Geometry Steers How Platinum Anticancer Candidates Grip DNA
A new study shows that changing how diphosphine ligands coordinate to cyclometalated platinum(II) complexes switches their DNA-binding mode from attempted ...
Cancer Drug Shortages Persist Nationwide, NCCN Survey of Top Centers Finds
A new NCCN survey finds that every responding US cancer center is facing at least one cancer drug shortage, with ...
Bladder Cancer Breakthrough: BH3 Mimetics Make Cisplatin Deadly Again
New research shows that BH3 mimetic drugs targeting antiapoptotic Bcl-2 family proteins can sensitize bladder cancer cells and patient-derived tumor ...
Splicing Factor LUC7L2 Emerges as a Driver of Kidney Damage from Chemotherapy
New research reveals that the RNA splicing factor LUC7L2 drives ferroptotic kidney damage from cisplatin by corrupting the splicing of ...
Cryo-EM Reveals How RNA Polymerase II Remodels and Stalls at Cisplatin DNA Crosslinks
Cryo-electron microscopy captures RNA polymerase II remodeling cisplatin-induced DNA interstrand crosslinks into a novel conformation that blocks the active site, ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!