PSMA-PRED protocol plans biomarker search for lutetium-PSMA treatment response
The French PSMA-PRED protocol plans to profile tumor DNA, RNA and methylation in 120 patients to identify candidate biomarkers associated ...
Tag: circulating tumor DNA
Whole-genome liquid biopsy predicts early lung cancer recurrence
A patient-specific whole-genome liquid biopsy detected lung cancer DNA associated with recurrence months before tumors became visible on imaging in ...
ctDNA Patterns Track Genomic Risk and Treatment Response in Advanced Breast Cancer
An exploratory BRIGHT-2 trial analysis associated longitudinal ctDNA patterns with prognosis, molecular response and candidate resistance alterations in advanced breast ...
Comment Questions Robustness of Deprivation Links in Breast Cancer Genomics
A 2026 correspondence questions the robustness of reported links between neighborhood deprivation, metastatic breast cancer genomics, targeted treatment use and ...
Review maps ctDNA-guided ESR1 treatment sequencing in advanced breast cancer
A review evaluates circulating tumor DNA testing for detecting ESR1-mutant clones and organizing treatment sequencing in hormone receptor-positive, HER2-negative advanced ...
Persister cells hiding in minimal residual disease drive cancer relapse
A new review outlines how drug-tolerant persister cells hidden within minimal residual disease drive cancer relapse and how pathway inhibitors, ...
How Breast Cancer Cells Outsmart Hormone Therapy—and the New Drugs Fighting Back
A new review details how ESR1 mutations, bypass signaling, and cell-cycle escape drive endocrine resistance in the most common breast ...
Structure-Guided Drug Firmonertinib Delivers Durable Responses in EGFR PACC-Mutated Lung Cancer
The concept of grouping EGFR mutations by structural rather than purely positional criteria represents a meaningful shift in how oncologists ...
Cancer’s Hidden Fingerprints: Tumor DNA Found in Body Fluids Beyond Blood
A new study shows that sequencing tumor DNA in ascites, pleural fluid, cerebrospinal fluid, and pericardial effusions can detect malignancies ...
Catching Pancreatic Cancer Early: Biomarkers, AI and Smarter Screening Offer New Hope
A new review outlines how genetic risk profiling, new-onset diabetes screening, advanced imaging, liquid biopsy biomarkers and artificial intelligence are ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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