New Open-Source Tool Hunts Ultra-Rare Cancer DNA Fingerprints in Blood
Researchers in Groningen developed MNVista, an open-source Bayesian tool that detects multi-nucleotide variants in sequencing data to identify circulating tumor ...
Tag: circulating tumor DNA
Blood Test for Tumor DNA Predicts Survival After Cancer Treatment Before Surgery
A meta-analysis of 41 studies and 3,058 patients shows that detectable circulating tumor DNA after neoadjuvant therapy strongly predicts worse ...
Blood Test Could Replace Tumor Biopsies for Personalized Cancer Immunotherapy
A new study in Cancer Discovery shows that circulating tumor DNA and immune cells drawn from a simple blood sample ...
Right-Sizing HER2-Positive Breast Cancer Treatment: New Algorithms Reshape Care Across the Disease Continuum
A new Nature Reviews Clinical Oncology review charts how HER2-targeted therapies, led by trastuzumab deruxtecan, are driving a shift from ...
Blood Clones That Masquerade as Cancer: New Framework Draws Hard Lines in Precision Oncology
A new framework in the Journal of Translational Medicine defines when blood-cell clones should be treated as sequencing artifacts, host ...
Genetic Barcodes Reveal What Tumor Biopsies Miss
By tagging breast cancer clones with unique genetic barcodes, researchers have quantified exactly how much tumor diversity needle biopsies and ...
Who Needs Intensive Lung Cancer Therapy? New Algorithm Aims to Match EGFR-Mutant Patients to the Right First Treatment
A new review proposes a risk-adapted algorithm to help clinicians decide which patients with advanced EGFR-mutant lung cancer need intensive ...
Blood Test and Scans Combined Reveal Hidden Patchiness in Advanced Melanoma
A longitudinal study of advanced melanoma patients shows that circulating tumor DNA tracks tumor burden and radiologic response, but its ...
Immune Therapy Plus Chemotherapy Erases Stage IIIB Lung Tumor Before Surgery
A stage IIIB lung squamous cell carcinoma patient achieved a pathological complete response after neoadjuvant sugemalimab plus chemotherapy, with biomarker ...
Spatiotemporal Framework Aims to Reshape Precision Care for Gastric and Colorectal Cancers
A review in LabMed Discovery proposes an adaptive, closed-loop precision management framework for gastric and colorectal cancers that combines spatial ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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