Cross-sectional survey links hepatitis B treatment burden to stopping thoughts
A cross-sectional survey links peginterferon adverse-effect burden and psychological distress with thoughts of stopping chronic hepatitis B treatment, while treatment ...
Tag: chronic hepatitis B
Serum CXCL-10 and CTLA-4 associated with inflammation in small treatment-naive chronic hepatitis B cohort
A small observational study found that serum CXCL-10 and CTLA-4 were associated with HBV viral load and histological inflammation in ...
Novel HEP-FIB score combined with machine learning models for non-invasive prediction of significant hepatic fibrosis in chronic hepatitis B patients: a single-center, internally validated study
A retrospective single-center study of 382 chronic hepatitis B patients found that the internally validated HEP-FIB score outperformed APRI, FIB-4 ...
Dual-Genotype Protein Yields Broader ELISA for Hepatitis B preS1 Antibodies
Researchers fused the preS1 regions of hepatitis B virus genotypes B and C into a single recombinant antigen, enabling an ...
Chemokine Gene Methylation Tied to Liver Inflammation in Chronic Hepatitis B
Researchers found that reduced methylation of the CXCL16 gene promoter in chronic hepatitis B patients tracks with elevated chemokine expression ...
Epigenetic Silencer Therapy Aims to Switch Off Viral DNA in Chronic Hepatitis B
An investigational epigenetic silencer therapy reported in Nature Biomedical Engineering aims to transcriptionally inactivate hepatitis B viral DNA by locking ...
Why Chronic Hepatitis B Still Defies a Functional Cure: New Review Maps the Immunological Barriers
A new review in Virology Journal explains how cccDNA persistence, viral genome integration and multi-level immune exhaustion keep functional cure ...
Losing Hepatitis B Surface Antigen Tied to Longer Survival Beyond Liver Health
A large prospective Chinese cohort study finds that sustained HBsAg seroclearance with very low HBV DNA is associated with lower ...
Epigenetic Editing Offers Safer Route to Functional Hepatitis B Cure
A new review argues that programmable epigenetic editors could functionally cure chronic hepatitis B by durably silencing viral cccDNA and ...
Chromatin Regulator ANKRD11 Emerges as Switch That Reinvigorates Exhausted T Cells
Researchers have identified ANKRD11 as a chromatin regulator whose loss reprograms CD8+ T cells to fight chronic hepatitis B and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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