H2A.Z reduction reshapes H3K27me3 at specific Arabidopsis loci
An Arabidopsis mutant study found that reduced H2A.Z altered H3K27me3 at hundreds of specific loci, with only a slight global ...
Tag: chromatin regulation
RNA Tag m6A Emerges as a Master Switch in Gene Control, Stress and Disease
A review in Nature Reviews Molecular Cell Biology explains how the RNA modification N6-methyladenosine regulates gene expression, enables cellular adaptation, ...
Cell study links resveratrol glucoside to mitochondrial and chromatin changes in senescence
An in-vitro study found that resveratrol glucoside reduced senescence-associated cellular changes by altering mitochondrial metabolism and chromatin regulation while showing ...
AML epigenetic therapies face network-driven resistance, review finds
A comprehensive review finds that AML cells commonly overcome epigenetic drugs through compensatory chromatin and transcriptional adaptation, favoring biomarker-selected combinations ...
BcEaf2 cofactor links histone methylation to fungal growth and virulence
A laboratory study links the BcEaf2 cofactor to BcSET2-dependent H3K36me3, revealing a regulatory module that supports fungal growth, stress adaptation, ...
Fungal wilt pathogen’s epigenetic toolkit mapped in first genome-wide HDAC survey
A genome-wide study has identified 11 histone deacetylase genes in Fusarium oxysporum, revealing how the devastating wilt pathogen uses epigenetic ...
Childhood Brain Tumor Study Exposes KDM2B as a Treatable Weak Spot in High-Risk Medulloblastoma
A comprehensive epigenetic analysis led by St. Jude and KiTZ identified the chromatin regulator KDM2B as an essential, selective dependency ...
Faulty Epigenetic Switch Disrupts Brain Cell Cycles and Drives White Matter Defects in Autism-Linked Disorders
New research shows that pathogenic variants in the chromatin regulator MSL2 disrupt oligodendrocyte precursor cell division and myelination through loss ...
Molecular Off Switch: Enzyme That Strips SUMO Tags Decides When Arabidopsis Seeds Wake Up
A new study shows that the SUMO protease ASP1 removes regulatory tags from the chromatin protein AL6, promoting its degradation ...
Master Switch Silenced: Distant DNA Element Holds Human Regulatory T Cells on Their Anti-Inflammatory Path
Researchers have identified a distal IRF4 chromatin regulatory element as the genomic control point that permits inflammation-induced reprogramming of human ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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