Sea Cucumber Fucoidan Eases Atherosclerosis in Mice by Rewiring Cholesterol Traffic
A sulfated fucoidan from the sea cucumber Pearsonothuria graeffei reduced arterial plaques and improved blood lipids in atherosclerosis-prone mice by ...
Tag: cholesterol metabolism
Lactate Fuels a Hidden Molecular Chain That Helps Liver Cancer Evade Immunity
A new study reveals how lactate-driven lactylation of histone and non-histone proteins in liver cancer activates a METTL3-FDFT1 cholesterol pathway ...
Cholesterol’s Hidden Geography: How Tumor Neighborhoods Fuel Resistant Prostate Cancer
A paired spatial multi-omics study of prostate cancer reveals that rising cholesterol during therapy tracks with castration resistance, as import-dominant ...
Cholesterol-Hungry Immune Cells May Decide Survival in Head and Neck Cancer
A multi-omics study finds that LDL cholesterol metabolism reshapes macrophages and tumor cells in head and neck squamous cell carcinoma, ...
Weight Loss Rewires Cholesterol Metabolism, but Tiny RNAs Are Not the Driver
A Dutch randomized trial finds that diet-induced weight loss shifts cholesterol metabolism in abdominally obese men from a synthesizing to ...
Aging Blunts a Protective Gut Lipid Defense That Keeps COVID-19 Mild
New research in aged hamsters shows that COVID-19 severity may hinge on an age-dependent failure of the gut to produce ...
Cholesterol Enzyme DHCR24 Emerges as Driver and Biomarker of Endometrial Cancer
New research identifies the cholesterol synthesis enzyme DHCR24 as a driver of endometrial carcinoma progression and a potential prognostic biomarker ...
AI Scours 1.2 Million Natural Products to Find Fungal Compound That Starves Glioblastoma of Cholesterol
An AI-driven screening pipeline identified the fungal sterol 5,6-epoxyergosterol as a selective LXRβ agonist that exploits the cholesterol dependency of ...
Coffee Diterpenes May Slow Sugar Digestion Without Acarbose-Like Side Effects
A new review proposes that coffee-derived diterpene esters, fatty acid conjugates and caffaldehydes may modulate intestinal alpha-glucosidase through membrane-anchored, non-competitive ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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