Circular RNA circuit driven by ALKBH5 fuels bile duct cancer growth
A team of researchers in China has mapped a previously hidden molecular circuit that helps one of the deadliest liver ...
Tag: cholangiocarcinoma
Hidden Bile Duct Tumor Masquerades as Gallstones in Landmark Case Report
A 63-year-old woman's recurrent abdominal pain was blamed on bile duct stones, but surgeons discovered a rare precancerous tumor hiding ...
Liver Transplants for Rare Bile Duct Cancer Show Strong Survival in Australia and New Zealand
A nationwide audit of 64 liver transplant patients with cholangiocarcinoma or mixed hepatocellular-cholangiocarcinoma confirms that very small intrahepatic tumours achieve ...
Two Endoscopic Techniques Team Up to Crack a Deadly Cancer
A Bulgarian team reports that combining endoscopic ultrasound with digital cholangioscopy achieved 96.2 percent diagnostic sensitivity in suspected bile duct ...
3D Tumor Models Expose How Biliary Tract Cancers Evade Chemotherapy
A new review argues that three-dimensional tumor models, including patient-derived organoids, can reveal the drug resistance and apoptosis evasion mechanisms ...
Biliary Tract Cancer Guidelines Excel at Clarity but Leave Precision Oncology Pathways Incomplete
A systematic review of 27 guideline families using AGREE II and AGREE-REX finds that clinical practice guidelines for precision oncology ...
Immunotherapy Boost for Bile Duct Cancer Survival Holds Firm After Three Years
Three-year follow-up of the phase 3 KEYNOTE-966 trial confirms that adding pembrolizumab to gemcitabine and cisplatin chemotherapy maintains a durable ...
Bile Sequencing Turns Discarded Fluid Into Early Cancer Clues
Ultra-low-pass whole-genome sequencing of cell-free DNA in bile collected during routine ERCP detected pancreatobiliary cancers with high specificity, identified the ...
Collagen Clue: How COL6A1 May Drive Bile Duct Cancer’s Deadly Spread
A new review in Cancer Reports proposes that the extracellular matrix protein COL6A1, overexpressed in the fibrotic stroma of cholangiocarcinoma, ...
New Trial Tests Oral Drug Plus Nanoliposomal Irinotecan for Hard-to-Treat Bile Duct Cancer
A German phase II trial called TRITICC-2 is testing whether oral trifluridine/tipiracil combined with nanoliposomal irinotecan can improve outcomes for ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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