Tag: chemotherapy resistance

New research shows that BH3 mimetic drugs targeting antiapoptotic Bcl-2 family proteins can sensitize bladder cancer cells and patient-derived tumor ...

A multicenter Central European real-world study finds sacituzumab govitecan delivers meaningful survival benefit and manageable toxicity in heavily pretreated metastatic ...

A new review maps how cancer-associated fibroblasts exclude immune cells from osteosarcoma tumors and outlines the therapeutic strategies that could ...

A new review reveals how the long non-coding RNA MIR99AHG acts as a multifunctional host gene and regulatory hub whose ...

New research reveals that the tight junction protein Claudin-1 stabilizes the ER chaperone calnexin through USP7-mediated deubiquitination, buffering lethal endoplasmic ...

A new systematic review finds that high intratumor heterogeneity, measured by single-cell sequencing and MRI radiomics, is consistently linked to ...

A new computational study shows that the plant flavonoid kaempferol and the chemotherapy drug docetaxel both bind strongly to the ...

A new review in Molecular Diversity maps how plant-derived natural products can induce iron-dependent ferroptosis and remodel the immune microenvironment ...

New laboratory research shows that canine hemangiosarcoma cell lines resist the chemotherapy drug temozolomide through a mechanism independent of the ...

Single-cell RNA sequencing of post-chemotherapy AML bone marrow has identified five macrophage polarization states whose abundance tracks with treatment response ...