Six-gene scoring system could help predict leukemia survival
Researchers in Barcelona report that a six-gene activity score, anchored by the Polycomb factor PHF19, divides acute myeloid leukaemia patients ...
Tag: chemotherapy resistance
miR-142-3p suppresses tumors but can reshape their surroundings
A 2026 review finds that miR-142-3p generally suppresses tumor-cell growth and improves drug response inside cancer cells, while its extracellular-vesicle ...
Retrospective colorectal cancer study links nerve invasion to metastasis
A retrospective Chinese cohort study found that perineural invasion in resected colorectal cancer was independently associated with distant metastasis and ...
Case report tracks aggressive pulmonary choriocarcinoma with brain metastases
A case report and small literature review found that serial β-HCG tracked disease progression in aggressive pulmonary choriocarcinoma, while checkpoint-inhibitor ...
Scientists Link a DNA-Building Enzyme to Fat Rewiring and Chemotherapy Failure in Pancreatic Cancer
A new study identifies RRM2 as a gene that connects nucleotide metabolism and SREBP1/FASN-driven lipid remodeling to gemcitabine resistance in ...
Rewiring the Tumor Engine: How Metabolism Could Become Cancer’s Next Weak Spot
New research highlights microRNAs, mitochondrial ribosomal proteins and lactate signaling as promising targets against cancer's metabolic reprogramming.
Pomegranate-Derived Polyphenol Ellagic Acid Boosts Oxaliplatin Against Colorectal Cancer, Study Finds
New research shows the plant polyphenol ellagic acid sensitizes wild-type TP53 colorectal tumors to oxaliplatin by suppressing ATM signaling and ...
Single-cell atlas reveals how hidden clones drive pancreatic cancer’s deadly evolution
A landmark single-cell and spatial transcriptomics study of 62 pancreatic tumors shows that genetically distinct clones within each cancer drive ...
Collagen Scaffold in Tumors Primes Colorectal Cancer Cells to Evade Chemotherapy
Patient-derived organoid and xenograft models reveal that a collagen I-rich tumor matrix activates TGFβ signaling and LTBP2 expression, priming colorectal ...
Rare Fusion Gene and WT1 Overexpression Define an Aggressive Leukemia Subtype
A newly reported leukemia case carrying both the rare DEK::CAN fusion gene and WT1 overexpression reveals how genetic synergy and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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