Neuropathology-centered approach opens new era for Alzheimer’s disease genetics
A new review argues that shifting Alzheimer's disease genetic research from clinically diagnosed cohorts to neuropathologically confirmed ones is revealing ...
Tag: Cerebral amyloid angiopathy
In Largest Study Yet, Hereditary Amyloidosis Reveals Its Hidden Impact on the Brain
A large Portuguese study of 151 patients with hereditary transthyretin amyloidosis shows that central nervous system complications, especially transient focal ...
Hidden Time Bias May Skew Evidence on Seizure Prevention After Brain Hemorrhage
A new letter in Neurocritical Care argues that immortal time bias may have distorted observational evidence on prophylactic antiseizure medication ...
Astrocyte Fibronectin Emerges as Key Driver of Blood–Brain Barrier Failure in Alzheimer’s Disease
A new Nature Aging study identifies astrocyte-derived fibronectin as the molecular link between the APOE ε4 allele, amyloid pathology, and ...
Unique amyloid-β filament structure found in APP Flemish mutation carriers
Cryo-electron microscopy has revealed an entirely new amyloid-β filament fold in the brains of individuals carrying one of the rarest ...
Symptomatic, Incidental DWI Lesions Show Distinct Risk Factors in Cerebral Amyloid Angiopathy
Cerebral amyloid angiopathy has long been defined by its most feared manifestation: bleeding into the brain. For decades, clinicians and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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