Patient-derived cancer models expand dependency maps but expose new limits
Hundreds of patient-derived cancer models expanded dependency mapping and revealed vulnerabilities linked to mutations, cellular states and treatment history, while ...
Tag: cellular plasticity
How Tumors Survive Radiation: Plastic Cells and Tolerant Niches Drive Recurrence
A new review in Molecular Cancer reframes radioresistance as an ecosystem-level phenomenon in which plastic residual tumor cells survive radiation ...
A Molecular License to Change: How One Gene Unlocks Natural Cell Identity Switching
New research in C. elegans reveals that the gene lin-15A enables natural cell identity conversion by weakening chromatin-based safeguards rather ...
Chemical Tags on mRNA Keep Pancreatic Alpha Cells From Turning Into Beta-Like Cells
New research shows that the mRNA modification m6A, installed by METTL14, is required to maintain pancreatic alpha-cell identity and prevent ...
Scientists Map the Master Plan for Rebuilding the Human Gut with Stem Cells
A landmark roadmap from the NIH-backed Intestinal Stem Cell Consortium details how intestinal stem cells and their niches could be ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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