Collagen Scaffold in Tumors Primes Colorectal Cancer Cells to Evade Chemotherapy
Patient-derived organoid and xenograft models reveal that a collagen I-rich tumor matrix activates TGFβ signaling and LTBP2 expression, priming colorectal ...
Tag: cell plasticity
Snail2 Emerges as the Master Switch Behind Partial EMT, Metastasis and Development
A comprehensive review in Cell Death Discovery maps how the transcription factor Snail2 governs partial epithelial-mesenchymal transition, driving both embryonic ...
A Molecular License to Change: How One Gene Unlocks Natural Cell Identity Switching
New research in C. elegans reveals that the gene lin-15A enables natural cell identity conversion by weakening chromatin-based safeguards rather ...
Chemical Tags on Messenger RNA Steer the Plasticity of Pancreatic Alpha Cells
A new Nature Metabolism study shows that m6A methylation of messenger RNA actively controls the plasticity of pancreatic alpha cells, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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