Cell division resets epigenetic marks to keep plant stem cells ready for branching
Active cell-cycle progression periodically resets repressive H3K27me3 marks in Arabidopsis bud precursor cells, keeping the meristem gene STM expressed, while ...
Tag: cell fate
Drosophila Stem Cell Debate Upended: Prospero Keeps Neuron Lineages on Track
New work shows that loss of the chromatin-binding protein Prospero leaves fly CNS cells of mixed identity that fail to ...
Seven-Chemical Cocktail Rewinds Human Stem Cells to an Eight-Cell Embryonic State
Researchers report that a seven-chemical cocktail rapidly converts human pluripotent stem cells into 8-cell-like cells that transcriptionally and functionally mirror ...
AI Reads Live Cell Videos to Predict Cancer Cell Fates Before They Happen
A Transformer deep learning model predicts cancer cell fates directly from live-cell videos with high accuracy up to eight hours ...
DNA Typewriter Records the Family Tree of Every Cell in a Developing Mouse Embryo
Scientists used a redesigned DNA Typewriter inserted into a fertilized mouse egg to record the lineage history of 1.3 million ...
Fruit Fly Glial Atlas Reveals How the Brain’s Support Cells Diversify
A single-cell atlas of the developing Drosophila visual system traces how glial cells diversify from larvae to adulthood and reveals ...
Single Transcription Factor PU.1 Rapidly Converts Fibroblasts into Macrophage-Lineage Cells
Researchers at Mie University show that the transcription factor PU.1 alone can rapidly reprogram fibroblasts into transplantable macrophage-lineage cells, bypassing ...
Cells Read Their Neighbors to Pinpoint Their Own Position in the Embryo
An information-theoretic study shows that gene expression in a cell's immediate neighbors supplies the missing positional information needed to uniquely ...
New AI Framework Puts Tissue Geography Into RNA Velocity and Steers Cell Fates In Silico
A new deep learning and agent-based framework called veloAgent integrates tissue spatial context into RNA velocity inference and enables virtual ...
Cell Shape and Position Predict Fate in a Developing Epithelium
By tracking thousands of cells in live Xenopus embryos and applying machine learning, researchers show that cell shape, position, and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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