Tag: CD4+ T cells

An interpretable machine learning framework called SPACER decodes the gene-level rules that recruit or exclude immune cells in tissues, revealing ...

A longitudinal study finds that older adults who recovered from COVID-19 mount weakened non-spike-specific Th1 CD4+ T cell responses to ...

An Oxford-developed single-allele chromatin mapping platform called MCCv identifies causal noncoding variants in autoimmune disease and reveals that a neo-CTCF ...

Using mass spectrometry-based immunopeptidomics, researchers identified 57 MHC-II peptides from 23 Francisella tularensis proteins and pinpointed ten immunogenic CD4 T ...

New research shows that bacterial proteins injected into gut epithelial cells, rather than those left on the bacterial surface, program ...

A new spatial transcriptomics study shows that tertiary lymphoid structures in tumors are spatially zoned immune organs whose core-periphery organization ...

Researchers in China have built a predictive model combining pre-treatment immune cell densities with clinical features to forecast recurrence after ...

Using patient-derived hepatocellular carcinoma organoids, researchers identified mITGB2, a splice-variant-derived peptide presented by MHC class II, as a functionally immunogenic ...

A large genetic analysis shows that asthma-linked gene regulation in CD4+ T cells changes with activation state, exposing dozens of ...

A cross-sectional study of sixty older people living with HIV finds that common hypomorphic variants of the STING1/TMEM173 gene are ...