Immune Cell Densities in Tumors May Predict Bladder Cancer Recurrence After BCG Therapy
Researchers in China have built a predictive model combining pre-treatment immune cell densities with clinical features to forecast recurrence after ...
Tag: CD4+ T cells
Organoid Platform Uncovers mITGB2 as a Promising CD4-Targeting Neoantigen in Liver Cancer
Using patient-derived hepatocellular carcinoma organoids, researchers identified mITGB2, a splice-variant-derived peptide presented by MHC class II, as a functionally immunogenic ...
T-Cell Activation State Reshapes Asthma Genetics and Points to New Drug Targets
A large genetic analysis shows that asthma-linked gene regulation in CD4+ T cells changes with activation state, exposing dozens of ...
Weakened STING Gene Variants May Ease Metabolic Burden of Aging with HIV
A cross-sectional study of sixty older people living with HIV finds that common hypomorphic variants of the STING1/TMEM173 gene are ...
BCL-2 Inhibition at Antiretroviral Therapy Start Shrinks Intact SIV Reservoir
Targeting the BCL-2 cell-survival pathway at the start of antiretroviral therapy reduced the pool of intact SIV proviruses in macaques, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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