Inflammatory Caspases Drive IL-33 Release From Skin in Atopic Dermatitis
A new study shows caspase-1/11 is required for IL-33 release from keratinocytes in vivo, and deleting these inflammatory caspases markedly ...
Tag: caspases
Thirty Years of reaper: How a Tiny Fly Gene Rewrote the Rules of Cell Death
A thirtieth-anniversary review traces how the discovery of reaper in Drosophila established IAP antagonism as a central principle of apoptosis ...
Gut Bacterial Brew Supercharges Chemotherapy Against Colorectal Cancer Cells in Lab Study
A cell-free supernatant from the probiotic bacterium Limosilactobacillus reuteri significantly enhanced 5-fluorouracil-induced apoptosis in colorectal cancer cells in vitro, suggesting ...
Bortezomib Triggers ROS-Driven Mitochondrial Cell Death and Blocks SKP2 Signaling in Skin T-Cell Lymphoma
New research shows the proteasome inhibitor bortezomib kills cutaneous T-cell lymphoma cells through ROS-dependent mitochondrial apoptosis while suppressing the SKP2-p21/p27 ...
Why Mature Human Sperm Resist TNF-α: The TNFR1 Apoptotic Shield Explained
New research shows that mature human spermatozoa resist TNF-α-induced apoptosis because their surface TNFR1 receptors cannot assemble the downstream signaling ...
Apoptosis Gene Patterns Reveal Distinct AML Subgroups and Flag BIK as a Surprising Prognostic Marker
A new study of 90 AML patients shows that apoptosis gene expression patterns define two biologically distinct leukemia subgroups with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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