SGLT2 Inhibitors Found to Repair Heart Metabolism Through Coenzyme A Pathway
New evidence shows SGLT2 inhibitors protect the failing heart by directly activating PANK1 to restore coenzyme A biosynthesis and myocardial ...
Tag: cardiac metabolism
Two-Timing Nanomedicine Rewires Heart Metabolism After a Heart Attack
Researchers developed a staged-release nanomedicine that coordinates early NAD+ replenishment with prolonged mitochondrial regulation to limit damage and preserve heart ...
Exercise Rewires Heart Metabolism Through a Single NADPH-Producing Pathway
A new Nature Metabolism study shows that exercise boosts cytosolic NADPH via the pentose phosphate pathway, driving healthy heart growth ...
Miniature Pig Heart Atlas Reveals a Unique Lipid-Burning Cardiomyocyte Subpopulation
The first single-cell atlas of the Wuzhishan miniature pig heart reveals a breed-specific lipid-metabolic cardiomyocyte subpopulation and a distinct transcriptional ...
Cytosolic NADPH Emerges as the Molecular Signal That Lets the Heart Mimic Exercise
New research in Nature Metabolism shows that raising cytosolic NADPH, a pentose phosphate pathway metabolite, recreates the heart-protective effects of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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