Low-Valine Diet Reduces Cardiac Hypertrophy in Hypertensive Male Rodents
A low-valine diet reduced pathological cardiac hypertrophy and improved cardiac function in hypertensive male rodents by limiting LONP1-mediated degradation of ...
Tag: cardiac hypertrophy
Circadian Clock Loss May Amplify Growth Hormone Signaling in the Heart
A minireview reports that cardiomyocyte-specific loss of the Bmal1 clock gene increases cardiac growth hormone sensitivity in mice, raising a ...
Astragaloside IV Emerges as a Candidate Ferroptosis Link in Heart Hypertrophy
Astragaloside IV reduces pathological cardiac hypertrophy and suppresses ferroptosis in separate models, but direct experiments are needed to establish whether ...
ZBED6 Loss Fuels Pathological Heart Enlargement Through a Newly Mapped Gene Switch
New research in PLOS Genetics identifies the ZBED6–MEOX1–ERK1/2 axis as a key regulator of pathological cardiac hypertrophy through impaired autophagy.
Exercise Rewires Heart Metabolism Through a Single NADPH-Producing Pathway
A new Nature Metabolism study shows that exercise boosts cytosolic NADPH via the pentose phosphate pathway, driving healthy heart growth ...
Cytosolic NADPH Emerges as the Molecular Signal That Lets the Heart Mimic Exercise
New research in Nature Metabolism shows that raising cytosolic NADPH, a pentose phosphate pathway metabolite, recreates the heart-protective effects of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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