CAR-T Cell Therapy Pushes Beyond Blood Cancers Into Solid Tumors and Autoimmune Disease
A sweeping review charts how CAR-T cell therapy has evolved from a blood cancer breakthrough into a versatile platform tackling ...
Tag: CAR-T Cell Therapy
Two Proteins Found on Nearly All Liver Cancer Cells Point to a Dual-Target CAR-T Strategy
A study of 140 liver tumor samples shows that Glypican-3 and AXL are co-expressed in nearly all hepatocellular carcinomas, supporting ...
From CAR-T Cells to Cancer Organoids: The Technologies Set to Transform Clinical Oncology
An editorial from Clinical Cancer Bulletin maps the converging technologies — TCR-T cells, cancer organoids, multi-specific antibody-drug conjugates, nanotechnology, and ...
Second CAR T-Cell Infusion Hits Myeloma After CELMoD Bridging
A German case report describes rapid deep response to ciltacabtagene autoleucel as a second BCMA-directed CAR T-cell therapy after mezigdomide-based ...
China’s Cancer Research Shifts From Molecular Reductionism to Holistic Integrative Medicine
A new review maps how Chinese cancer research has evolved from single-target molecular reductionism toward a three-tier holistic integrative medicine ...
Massive Single-Cell Atlas Maps Five Cancer Archetypes in Multiple Myeloma
A single-cell atlas of 341 multiple myeloma patients identifies five malignant transcriptional archetypes and an orthogonal proliferative program, enabling improved ...
Lipid Metabolism Emerges as a Central Driver of Drug Resistance in Aggressive Lymphoma
A new review argues that lipid metabolic reprogramming acts as a convergence node for treatment resistance in aggressive non-Hodgkin lymphoma, ...
FDA Clears Trial of Dual-Target CAR T-Cell Therapy for Colorectal Cancer
The FDA has cleared a CU Anschutz clinical trial testing dual-target CAR T-cell therapy against advanced colorectal cancer and pediatric ...
Scientists Decode Design Rules for Building More Potent Chimaeric Antigen Receptors
A new Nature Biomedical Engineering study maps the sequence and structural features that determine whether chimaeric antigen receptors signal effectively, ...
New CAR T therapy targets fusion-driven solid tumors via GPNMB
Chimeric antigen receptor T cell therapy has transformed the treatment of certain blood cancers, delivering remissions in patients with leukemia ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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