Blood Cell Crashes After CAR-T Therapy Follow a Predictable Risk Score, Study Finds
A retrospective cohort study of 96 patients shows the CAR-HEMATOTOX score predicts severe neutropenia and thrombocytopenia after CAR-T cell therapy, ...
Tag: CAR-T Cell Therapy
CAR-T Cells Linger in the Gut and Drive Severe Intestinal Inflammation, Mount Sinai Study Finds
Chimeric antigen receptor T cell therapy has redefined the treatment of multiple myeloma, offering deep and durable remissions to patients ...
CAR T-Cell Therapy May Spare Older Patients’ Memory More Than Younger Ones
A longitudinal study of 155 lymphoma patients found that older adults recovered memory function after CAR T-cell therapy while younger ...
Weill Cornell Medicine Lands Fall Grants to Attack Hard-to-Treat Cancers
New awards from the AACR, Department of Defense and National Cancer Institute will fund enhancer hub research, ovarian cancer immunotherapy, ...
Glioblastoma Pipeline Shifts to Biomarker-Guided Combination Therapies
A new Oncoscience perspective maps the 2025–2026 glioblastoma clinical trial pipeline across four mechanistic domains, showing how biomarker-guided selection and ...
MD Anderson Unveils Wave of Cancer Breakthroughs From Lung Immunotherapy to Microbiome Medicine
New MD Anderson studies report a Phase 3 immunotherapy advance in EGFR-mutant lung cancer, a dual role for B7-H3 in ...
Immune Rejection and Cell Fitness Shape Success of Off-the-Shelf CAR T Therapies
A new MD Anderson study finds that pre-existing immune rejection and the intrinsic fitness of donor-derived CAR T cells determine ...
UChicago Medicine Trials Homegrown Engineered T-Cell Therapy for Advanced Solid Tumors
UChicago Medicine has launched a first-of-its-kind investigator-initiated clinical trial of a fully on-site manufactured T-cell receptor therapy engineered to target ...
Brazil’s CAR T-cell revolution: why a $500,000 cancer cure remains out of reach for most patients
The clinical case for expanding access to CAR T-cell therapy in Brazil rests on a substantial body of evidence demonstrating ...
In vivo CAR T-cell therapy: a systematic review of clinical trials
The systematic review by Mahmoudi and colleagues arrives at a moment when the field of CAR T-cell therapy is confronting ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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