Engineered Dendritic Cell Vaccine Draws Immune Cells Into Lung Tumors but Falls Short of Shrinkage
A phase I trial found that a CCL21-engineered dendritic cell vaccine combined with pembrolizumab safely increased T cell infiltration in ...
Tag: cancer vaccine
Viral Mimicry Revealed: SARS-CoV-2 T Cells Also Recognize Tumor Antigens
Single-cell TCR sequencing shows that SARS-CoV-2-specific CD8 T cells recognize a tumor-associated antigen through molecular mimicry, supporting viral-mimic cancer vaccines.
Nanovaccine Built From Metal–Organic Frameworks Drives Tumours Into Full Retreat
A metal–organic framework nanovaccine co-delivering tumour antigens and STING agonists induced systemic tumour regression, immune memory and synergy with radiotherapy ...
IDO1 Inhibitor Plus Melanoma Vaccine Fails to Boost Tumor-Fighting T Cells in Trial
A phase II pilot trial found that the IDO1 inhibitor epacadostat safely reduced kynurenine-to-tryptophan ratios in advanced melanoma patients but ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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