Hidden Metabolic Trick Lets Myeloma Cells Steal Fuel to Survive a Key Cancer Drug
New research reveals that resistant myeloma cells import putrescine through the transporter SLC45A4, activating HOXA1-driven NF-kappaB signaling with help from ...
Tag: cancer metabolism
Fat-Processing Gene Variants Tied to Lymphoma Risk and Survival
A Chinese genetic association study links inherited variants in lipid metabolism genes to the risk, severity, treatment response, and survival ...
Fat-Filled Droplets Power the Deadliest Childhood Brain Tumours
New research shows that high-risk Group 3 and Group 4 medulloblastoma cells accumulate cholesterol ester-rich lipid droplets that support energy ...
Cancer’s Sphingolipid Code: How One Lipid Family Decides Cell Fate Across Tumors
A new review in Molecular Biology Reports maps how the ceramide–S1P balance and ganglioside signaling form a cancer-type-specific lipid code ...
Daphniphyllum-Derived Compound Starves Tumors of Energy to Block Their Self-Built Blood Vessels
Japanese researchers have shown that 22-benzyloxydaphlongaminone, a synthetic intermediate of the Daphniphyllum alkaloid isodaphlongamine H, blocks vasculogenic mimicry in lung ...
Fasting Starves Tumors of Taurine, Triggering Immune Cell Death in Colorectal Cancer
A new study shows intermittent fasting depletes taurine, destabilizes the PERK stress pathway in colorectal cancer cells, and triggers immunogenic ...
LSU Health New Orleans Hires Star Radiation Oncologist to Build First Academic Department
LSU Health New Orleans has recruited radiation oncologist Dr. Puneeth Iyengar from Memorial Sloan Kettering to establish its first academic ...
Famed brain cancer drug turns out to hit a metabolic enzyme, not its intended target
A comprehensive chemical biology study shows that the celebrated KDM4 inhibitor QC6352 and its clinical analog zavondemstat kill glioblastoma stem ...
Precision Nutrition: Tailoring Diet to Cancer Treatment Could Redefine Precision Medicine
A new narrative review argues that individualized dietary interventions, grounded in tumor metabolism and the gut microbiome, should be integrated ...
How Broken Mitochondria Send Cancer Cells Into Survival Mode
A new review details how disrupted mitochondrial homeostasis and activated retrograde signaling drive cancer progression and may open fresh therapeutic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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