Splicing Factor SRSF7 Emerges as a Master Switch Behind Triple-Negative Breast Cancer Spread
Researchers in the Netherlands identified the RNA splicing factor SRSF7 as a key regulator of migration, invasion, and lung metastasis ...
Tag: cancer genomics
New Browser-Based Toolkit Runs Cancer Mutational Signature Analysis Without Installing a Thing
A new open-source JavaScript toolkit called mSigSDK brings multi-tool mutational signature analysis, privacy-preserving local computation, and reproducible reporting directly into ...
Tiny DNA Insert in a Super-Enhancer Fine-Tunes Two Cancer Genes in Breast Tumors
A common germline insertion within a bifunctional super-enhancer dampens the expression of the cancer-promoting genes LINC00636 and CD47 in breast ...
Mapping STING Mutations to Unlock Immunity and New Therapies
A comprehensive atlas of STING mutations consolidates genetic, structural, and clinical data to clarify how variants drive autoinflammation, immunodeficiency, and ...
Four Asia-Pacific Nations, Four Paths: Why Cancer Genomics Success Hinges on Health Systems, Not Sequencers
A landmark comparative review finds that Japan, South Korea, China, and Australia have all mastered the technology of cancer genomics, ...
Mutational Fingerprints Reveal the Hidden Forces Driving Prostate Cancer
A new Nature study integrates multiple classes of genomic mutations to define the distinct mutational processes that shape prostate cancer ...
Single-Cell Multi-Omics Reveals How Cancer Clones Evolve Genotype and Phenotype Together
A Nature Reviews Cancer review explains how genotype-aware single-cell multi-omics and phylogenetic reconstruction are revealing how mutant clones in healthy ...
Reading the Evolutionary History of Cancer Written in Tumour Genomes
A Nature Reviews Cancer review argues that population genetics offers the mathematical framework needed to turn tumour genome sequencing data ...
CnQuant Enables High-Resolution Chromosomal Copy Number Profiling for Precision Oncology Clinics
A new open-source software platform could bring high-resolution chromosome analysis closer to routine cancer care, allowing clinicians to inspect tumor ...
Global Cancer Genomics Enabled by Centralized Processing of Frozen Tumor Tissues
Cancer researchers have unveiled a standardized pathology and molecular workflow designed to solve one of the most difficult problems in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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