Tag: cancer genomics

A common germline insertion within a bifunctional super-enhancer dampens the expression of the cancer-promoting genes LINC00636 and CD47 in breast ...

A comprehensive atlas of STING mutations consolidates genetic, structural, and clinical data to clarify how variants drive autoinflammation, immunodeficiency, and ...

A landmark comparative review finds that Japan, South Korea, China, and Australia have all mastered the technology of cancer genomics, ...

A new Nature study integrates multiple classes of genomic mutations to define the distinct mutational processes that shape prostate cancer ...

A Nature Reviews Cancer review explains how genotype-aware single-cell multi-omics and phylogenetic reconstruction are revealing how mutant clones in healthy ...

A Nature Reviews Cancer review argues that population genetics offers the mathematical framework needed to turn tumour genome sequencing data ...

A new open-source software platform could bring high-resolution chromosome analysis closer to routine cancer care, allowing clinicians to inspect tumor ...

Cancer researchers have unveiled a standardized pathology and molecular workflow designed to solve one of the most difficult problems in ...

Laura J. Tafe, M.D., a professor of pathology and laboratory medicine at Dartmouth Hitchcock Medical Center and the Geisel School ...

Cancer treatment is undergoing a profound transformation as molecular classification reshapes therapeutic strategies. Yet, despite advances, many pivotal oncogenic drivers ...