Calreticulin Is Not the MHC Class I Gatekeeper Immunology Textbooks Claimed
A new study finds that calreticulin, long considered an essential chaperone for MHC class I antigen presentation, is functionally expendable ...
Tag: calreticulin
Safer Macrophage-Based Immunotherapy Combo Shows Promise Against Ewing Sarcoma
Researchers have replaced the toxic components of a macrophage-directed immunotherapy for Ewing sarcoma with cyclophosphamide and the erythrocyte-sparing antibody lemzoparlimab, ...
Cell Death Turns Tumors Against Themselves in Combo Therapy for Pancreatic Neuroendocrine Cancer
New research shows that combining sunitinib with 177Lu-DOTATATE radiotherapy triggers immunogenic cell death in pancreatic neuroendocrine tumors, recruiting antitumor T ...
Light-Activated Cancer Therapy Shows Power to Trigger Body-Wide Immune Attack on Tumors
A systematic review of preclinical studies finds that photodynamic therapy can induce systemic antitumor immunity and abscopal effects, especially when ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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