Stiffer 3D Gels Make Insulin-Secreting Cells Work Harder Through Piezo1
The choice of hyaluronic acid methacrylate as the scaffold material for this study reflects a deliberate design decision that deserves ...
Tag: calcium signaling
Boldine, an alkaloid from Chilean boldo tree, shields diabetic muscle from damage
A Chilean-led study shows the boldo-derived alkaloid boldine blocks large-pore channels in muscle cells, preventing diabetes-induced muscle weakness, lipid accumulation ...
Sea Snail’s Strange Sperm Release Their Secret Cargo in a Calcium-Triggered Burst
New research reveals how non-fertilizing parasperm in the strawberry conch discharge globular bodies through calcium-dependent exocytosis, a process controlled separately ...
Damaged Mitochondrial DNA Emerges as a Central Driver of Pulmonary Arterial Hypertension
A new review argues that oxidized mitochondrial DNA acts as both a persistent inflammatory signal and a potential biomarker driving ...
PFOA Replacements Found to Sabotage Human Sperm Through Calcium and Mitochondrial Damage
A new in vitro study shows that HFPO compounds marketed as safer PFOA replacements impair human sperm motility, acrosome reaction ...
NFAT Transcription Factors Emerge as Central Drivers of Pulmonary Hypertension
A new review in Molecular Biology Reports synthesizes evidence that NFAT1-4 transcription factors drive the abnormal proliferation of pulmonary artery ...
Resveratrol Shields the Epileptic Brain by Rewiring Ion Channel Genes, Rat Study Finds
A new rat study shows that resveratrol slows epilepsy development and protects the hippocampus by restoring SIRT1 signaling and rebalancing ...
Scientists Discover a Lipid-Gated Calcium Channel That Drives Diabetic Kidney Damage
A new study identifies a ceramide-gated Calhm2 calcium influx pathway, driven by Aebp1, that injures podocytes in diabetic kidney disease ...
How a Single Glycolytic Enzyme Decides Whether Cancer Cells Grow or Senesce
A new study in Advanced Science shows that losing the glycolytic enzyme TPI1 causes DHAP to accumulate and activates a ...
Calcium-Sensing Genes Traced to the Roots of Plant Life on Land
A new phylogenomic study of 86 green plant species traces how the calcium-dependent protein kinase gene family originated, expanded, and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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