Mutations in a Fly Ceramide Enzyme Reveal How Sphingolipids Steer Insulin Resistance
Precise mutations in the fruit fly's sole ceramide synthase either worsen or partially ease high-sugar-diet insulin resistance, linking sphingolipid composition ...
Tag: BMC Biology
Low Oxygen Helps Early Embryos Switch On Their Genes, Mouse Study Finds
A new mouse study shows that hypoxic culture enhances zygotic genome activation by increasing H3K4me3 at zygotic gene promoters and ...
Fat Body Hormone SPARC Drives Insulin Release and Body Growth in Fly Larvae
A new BMC Biology study identifies the fat body-secreted matricellular protein SPARC as an evolutionarily conserved, incretin-like signal that promotes ...
Piranha Pineal Glands Reveal How Ancient Genome Duplication Diversified Fish Light Sensors
Researchers have found that the red piranha retains two duplicated parietopsin genes whose proteins absorb similar green light but trigger ...
Insulin-Sensing FOXO Protein Guards the Genome After DNA Damage
New research in C. elegans shows that the FOXO transcription factor DAF-16 directly activates DNA repair genes to preserve genome ...
Deep Learning Tool Reads RNA Tails Straight From Nanopore Signals
A new deep learning framework called PolyAnalysis estimates RNA poly(A) tail lengths directly from raw nanopore sequencing signals and profiles ...
Your Brain Learns New Weight Clues as Fast as Familiar Ones
A Durham University study finds that the brain's grip force predictions can rapidly learn arbitrary visual weight cues, whether shown ...
Scientists Reverse-Engineer Insect Smell Receptors to Identify Moth Sex Pheromones
INRAE researchers used AI-predicted olfactory receptor structures to identify, for the first time, the sex pheromone of the lily moth, ...
Splicing Complex Tied to Cell Fate Decisions in Developing Worms
A new study in C. elegans shows that a conserved CYL-1/CDK-11/EELO-1 complex couples pre-mRNA splicing and transcription to embryonic cell ...
Centuries of Sheep Drives Left Their Mark in the DNA of Iberian Herding Dogs
A genomic study of 445 Iberian livestock dogs shows that centuries of transhumance preserved high genetic diversity and blurred the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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